Benzalkonium chloride
Benzalkonium chloride is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
73 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glaucoma | D005901 | EFO_0000516 | H40 | — | — | 1 | 4 | 1 | 6 |
| Ocular hypertension | D009798 | EFO_1001069 | H40.0 | — | — | 1 | 3 | 1 | 5 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | 1 | 1 | 1 | 3 |
| Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | — | — | 1 | 1 | 1 | 3 |
| Low tension glaucoma | D057066 | EFO_1001022 | H40.12 | — | — | — | 1 | — | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Benzalkonium chloride |
| INN | benzalkonium chloride |
| Description | Benzalkonium chloride (BZK, BKC, BAK, BAC), also known as alkyldimethylbenzylammonium chloride (ADBAC) and by the trade name Zephiran, is a type of cationic surfactant. It is an organic salt classified as a quaternary ammonium compound. ADBACs have three main categories of use: as a biocide, a cationic surfactant, and a phase transfer agent. ADBACs are a mixture of alkylbenzyldimethylammonium chlorides, in which the alkyl group has various even-numbered alkyl chain lengths.
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| Classification | Small molecule |
| Drug class | quaternary ammonium derivatives; quaternary ammonium derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1.[Cl-] |
Identifiers
| PDB | — |
| CAS-ID | 8001-54-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL502109 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | F5UM2KM3W7 (ChemIDplus, GSRS) |
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Safety
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487 adverse events reported
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