Benzalkonium chloride
Benzalkonium chloride is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
71 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glaucoma | D005901 | EFO_0000516 | H40 | — | 1 | 2 | 9 | 2 | 14 |
| Ocular hypertension | D009798 | EFO_1001069 | H40.0 | — | 1 | 1 | 4 | 1 | 7 |
| Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | — | 1 | 1 | 4 | 1 | 7 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | 1 | 1 | 2 | 1 | 5 |
| Healthy volunteers/patients | — | — | — | 1 | 1 | — | 1 | 2 | 5 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | 2 | 2 | 5 |
| Communicable diseases | D003141 | — | — | — | — | — | 1 | 2 | 3 |
| Dry eye syndromes | D015352 | — | H04.12 | — | — | 1 | 2 | — | 3 |
| Eye diseases | D005128 | EFO_0003966 | H44 | 1 | — | — | 1 | — | 2 |
| Respiratory tract infections | D012141 | — | J06.9 | — | — | — | 1 | 1 | 2 |
Show 17 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Uveitis | D014605 | HP_0000554 | H20.9 | — | — | 1 | — | 1 | 2 |
| Anterior uveitis | D014606 | EFO_1000811 | — | — | — | 1 | — | 1 | 2 |
| Iridocyclitis | D015863 | HP_0001094 | H20 | — | — | 1 | — | 1 | 2 |
| Corneal ulcer | D003320 | — | H16.0 | — | 2 | 2 | — | — | 2 |
| Keratitis | D007634 | HP_0000491 | H16 | — | 2 | 2 | — | — | 2 |
| Ulcer | D014456 | MPATH_579 | — | — | 2 | 2 | — | — | 2 |
| Bacterial conjunctivitis | D003234 | EFO_1000829 | H10.0 | — | — | 1 | — | — | 1 |
| Conjunctivitis | D003231 | HP_0000509 | H10 | — | — | 1 | — | — | 1 |
| Corneal diseases | D003316 | — | H18.9 | — | — | 1 | — | — | 1 |
| Syndrome | D013577 | — | — | — | — | 1 | — | — | 1 |
Show 4 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | — | 2 | — | — | 1 | 3 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | 2 | — | — | — | 2 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | 2 | — | — | — | 2 |
| Covid-19 | D000086382 | — | — | 1 | 1 | — | — | — | 2 |
| Cystinosis | D003554 | — | E72.04 | — | 1 | — | — | — | 1 |
| Hypersensitivity | D006967 | HP_0012393 | T78.40 | — | 1 | — | — | — | 1 |
| Rhinitis | D012220 | EFO_0008521 | J31 | — | 1 | — | — | — | 1 |
| Myopia | D009216 | EFO_0003927 | H52.1 | — | 1 | — | — | — | 1 |
| Sepsis | D018805 | HP_0100806 | A41.9 | — | 1 | — | — | — | 1 |
| Hematopoietic stem cell transplantation | D018380 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alcoholism | D000437 | EFO_0003829 | F10.1 | 1 | — | — | — | — | 1 |
| Alcohol-related disorders | D019973 | — | F10 | 1 | — | — | — | — | 1 |
| Presbyopia | D011305 | — | H52.4 | 1 | — | — | — | — | 1 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Aortic valve stenosis | D001024 | HP_0001650 | — | — | — | — | — | 2 | 2 |
| Cataract | D002386 | HP_0000518 | H26.9 | — | — | — | — | 1 | 1 |
| Macular edema | D008269 | — | — | — | — | — | — | 1 | 1 |
| Iritis | D007500 | EFO_1000997 | — | — | — | — | — | 1 | 1 |
| Chronic renal insufficiency | D051436 | — | N18 | — | — | — | — | 1 | 1 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | — | — | 1 | 1 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | — | — | — | 1 | 1 |
| Hyperparathyroidism | D006961 | EFO_0008506 | E21.3 | — | — | — | — | 1 | 1 |
| Secondary hyperparathyroidism | D006962 | EFO_1001173 | — | — | — | — | — | 1 | 1 |
| Respiratory signs and symptoms | D012818 | — | — | — | — | — | — | 1 | 1 |
Show 7 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Benzalkonium chloride |
| INN | benzalkonium chloride |
| Description | Benzalkonium chloride (BZK, BKC, BAK, BAC), also known as alkyldimethylbenzylammonium chloride (ADBAC) and by the trade name Zephiran, is a type of cationic surfactant. It is an organic salt classified as a quaternary ammonium compound. ADBACs have three main categories of use: as a biocide, a cationic surfactant, and a phase transfer agent. ADBACs are a mixture of alkylbenzyldimethylammonium chlorides, in which the alkyl group has various even-numbered alkyl chain lengths.
|
| Classification | Small molecule |
| Drug class | quaternary ammonium derivatives; quaternary ammonium derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1.[Cl-] |
Identifiers
| PDB | — |
| CAS-ID | 8001-54-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL502109 |
| ChEBI ID | — |
| PubChem CID | 3014024 |
| DrugBank | — |
| UNII ID | F5UM2KM3W7 (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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Adverse Events
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464 adverse events reported
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